Медицинская литература. Новинки

 

 

 

 

 

 

КЛИНИЧЕСКИЙ СЛУЧАЙ АУТОИММУННОГО ПОЛИГЛАНДУЛЯРНОГО СИНДРОМА ВТОРОГО ТИПА

Вы можете загрузить полный текст статьи в формате pdf

В статье приводится клиническое наблюдение молодой женщины с аутоиммунным полигландулярным синдромом 2-го типа, представленным первичной недостаточностью коры надпочечников и нарушением функции щитовидной железы. В ходе течения заболевания произошло изменение функциональной активности щитовидной железы со сменой гипотиреоза на тиреотоксикоз, что стало причиной резкой декомпенсации надпочечниковой недостаточности

Ключевые слова:
аутоиммунный полигландулярный синдром 2-го типа, гипотиреоз, гипертиреоз, надпочечниковая недостаточность.

Литература:
1. Bhandarkar S.D., Retnam V.J. Hyperthyroidism following
hypothyroidism. J. Postgrad. Med. 1980; 26 (1): 90–94.
2. Dittmar M., Kahaly G.J. Polyglandular autoimmune syndromes:
Immunogenetics and longterm followup. J. Clin. Endocrinol.
Metab. 2003; 88 (7): 2983–2992.
3. Eisenbarth G.S., Gottlieb P.A. Autoimmune polyendocrine syndromes. N. Engl. J. Med. 2004; 350 (20): 2068–2079.
4. Kahaly G.J. Polyglandular autoimmune syndromes. Eur. J. Endocrinol. 2009; 161 (1): 11–20.
5. Kang B.H. Changes in thyroidstimulating and TSH-binding
inhibitory activities in a patient who developed hyperthyroidismdue to Graves' disease following primary hypothyroidism. Clin.
Endocrinol. (Oxf.) 1986; 25 (5): 519–525.
6. Kasagi K., Konishi J., Iida Y., Mori T., Torizuka K. Changes in thyroidstimulating and TSHbinding inhibitory activities in a patient who developed hyperthyroidism due to Graves' disease following
primary hypothyroidism. Clin. Endocrinol. (Oxf.) 1986; 25 (5):
519–525.
7. Lesho E., Jones R.E. Hypothyroid Graves' disease. South Med. J.
1997; 90 (12): 1201–1203.
8. OsorioSalazar C., Lecomte P., Madec A.M., Baulieu J.L. Basedow
disease following autoimmune primary hypothyroidism. Apropos
of 7 cases. Ann. Endocrinol. 1994; 55 (5): 185–189.
9. Takasu N., Matsushita M. Changes of TSH-stimulation blocking
antibody (TSBAb) and thyroid stimulating antibody (TSAb) over
10 years in 34 TSBAb-positive patients with hypothyroidism
and in 98 TSAb-positive Graves' patients with hyperthyroidism:
Reevaluation of TSBAb and TSAb in TSH-receptor-antibody
(TRAb)-positive patients. J. Thyroid. Res. 2012: 182176.
10. Takasu N., Yamada T., Sato A. et al. Graves' disease following
hypothyroidism due to Hashimoto's disease: studies of eight cases.
Clin. Endocrinol. (Oxf.) 1990; 33 (6): 687–698.
11. Zellman H.E., Sedgwick C.E. Hashimoto's thyroiditis and Graves'
disease coincidental occurrence. Lahey Clin. Foundation Bull.
1966; 15: 53–58.

A clinical case of autoimmune polyglandular syndrome type 2

This article describes the case of a young woman with autoimmune polyglandular syndrome type 2, presented by the primary adrenal insufficiency and thyroid dysfunction. In the course of the disease there was a change of the thyroid functional activity from hypothyroidism to hyperthyroidism, which led to adrenal insufficiency decompensation

Keywords:
autoimmune polyglandular syndrome type 2, hypothyroidism, hyperthyroidism, adrenal insufficiency