Медицинская литература. Новинки

 

 

 

 

 

 

Особенности проведения радиочастотной термоабляции злокачественных опухолей печени. Обзор литературы

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В статье приведены сводные данные отечественных и зарубежных авторов об особенностях определения показаний к проведению радиочастотной термоабляции (РЧА) у больных с первичным и метастатическим раком печени. Вопрос лечения больных с гепатоцеллюлярным раком печени и метастазами в печени злокачественных опухолей иной первичной локализации остается весьма актуальным по причине высокого уровня заболеваемости. Хирургическое лечение при злокачественных опухолях печени сегодня остается методом выбора и существенно улучшает выживаемость таких больных. Однако операбельность при злокачественном поражении печени не превышает 10–15% т.е. более 80% больных нуждаются в нехирургическом противоопухолевом воздействии. В ряду технологий нехирургического лечения в настоящее время широко применяется метод РЧА как хорошо контролируемый, миниинвазивный и достаточно эффективный способ разрушения опухолевых узлов. Результаты лечения больных со злокачественным опухолевым поражением печени с применением РЧА обнадеживающие, но свой лечебный потенциал методика реализует лишь при строгом соблюдении показаний.

Ключевые слова:
рак печени, первичный рак пече ни, метастазы рака в печень, радиочастотная термоаб ляция опухолей печени.

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Peculiarity of Radio-Frequency Thermoablation Procedure for Liver Cancer. Review

Purpose. To review the current application of RFA and the peculiarity of this procedure in the treatment of a primary and metastatic liver cancer. Background. The problem of hepatocellular carcinoma and liver metastases treatment still remains actual because of high level of incidence. Surgical treatment for liver cancer is the most effective way to increase a survival today. At the same time, operability for liver cancer doesn’t exceed 10–15% i.e. over 80% of patients need in not surgical methods of treatment. For inoperable liver cancer several of local destructive technologies are used. Among them the priority remains for radio-frequency thermoablation (RFA), as well controlled, minimal invasive and effective method of tumors destruction. Summary. The results of an application of RFA in the treatment of patients with malignant liver tumor are very encouraging but the best result may be obtained only at strict observance of indications.

Keywords:
liver cancer, hepatocellular carcinoma, liver metastases, radiofrequency ablation (thermoablation).