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Под нестабильной подразумевается бляшка, склонная к разрыву, которая может привести к тромбозу коронарной артерии с развитием острого коронарного синдрома. Инфаркт миокарда часто происходит у пациентов, которые имеют средний риск неблагоприятных кардиоваскулярных событий, причем тромбоз часто происходит в поражениях коронарных артерий с умеренно выраженной степенью стеноза. Таким образом, в большинстве случаев такие бляшки клинически себя никак не проявляют до развития острого события, а также не подлежат реваскуляризации согласно актуальным рекомендациям. Одним из важных вопросов является выявление нестабильных бляшек с целью разработки мер профилактики. Внутрисосудистый ультразвук с виртуальной гистологией - полезный и эффективный метод выявления нестабильных бляшек, который позволяет определить категорию пациентов с высоким риском неблагоприятных коронарных событий.
Ключевые слова:
атеросклероз, нестабильная бляшка, ВСУЗИ, atherosclerosis, vulnerable plaque IVUS
Литература:
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The vulnerable plaque is an atherosclerotic plaque which can lead to thrombosis of a coronary artery with development of an acute coronary syndrome. Most myocardial infarctions occur in people with average levels of risk factors and thrombosis mostly originate from lesions that are less severely narrowed. Thus, in most cases, these plaques are clinically silent before the “unheralded” acute event and would not be considered eligible for preventive treatment based on current guidelines. The main question is to identify thrombosis-prone “vulnerable” plaques before they rupture or become destabilized. IVUS is a useful tool in identifying high risk plaque features and vulnerable lesions in patients.
Keywords:
атеросклероз, нестабильная бляшка, ВСУЗИ, atherosclerosis, vulnerable plaque IVUS
