Медицинская литература. Новинки

 

 

 

 

 

 

Прогнозирование тяжелых после опера ционных осложнений в хирургии поджелудочной железы с помощью шкалы PREPARE: одноцентровое наблюдательное исследование

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Цель. Оценка эффективности шкалы PREPARE в прогнозировании тяжелых осложнений после операций на поджелудочной железе. Материал и методы. В исследование “случай-контроль” включали оперированных на поджелудочной железе. Осложнения ?II степени по Clavien-Dindo были обозначены как “тяжелые”. Пациентов разделили на 2 группы: “0-II степень” (контроль) и “III-V степень” (случай). Для всех больных были подсчитаны баллы и определены категории риска по шкале PREPARE. Результаты. Был включен 151 пациент: “0-II степень” - 102 (68%) наблюдения, “III-V степень” - 49 (32%). Использовали ROC-анализ: для баллов (AUC = 0,616; 95% ДИ 0,527-0,706; р = 0,014) и для категорий риска (AUC = 0,555; 95% ДИ 0,463-0,648; р = 0,241) шкалы PREPARE. Заключение. Полученные данные не позволяют в настоящее время

Ключевые слова:
поджелудочная железа, резекция, осложнения, PREPARE, прогнозирование, pancreas, resection, complications, PREPARE, prognosis

Литература:
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Prediction of severe postoperative complications in pancreatic surgery using the Preoperative Pancreatic Resection (PREPARE) score: a single-center observational study

Aim. To evaluate the effectiveness of the PREPARE score in predicting severe complications after pancreatic surgery. Materials and Methods. The case-control study included patients operated on the pancreas. Grade ?III Clavien- Dindo complications were designated as “severe”. Patients were divided into two groups: “0-II degree” (control) and “III-V degree” (case). For all patients, scores were calculated, and risk categories were determined according to the PREPARE score. Results. The study included 151 patients: “0-II degree” - 102 (68%) observations, “III-V degree” - 49 (32%). ROC analysis was used for the scores (AUC = 0.616; 95% CI 0.527-0.706; p = 0.014) and for the risk categories (AUC = 0.555; 95% CI 0.463-0.648; p = 0.241) of the PREPARE score. Conclusion. The obtained data do not currently enable us to recommend the PREPARE score for predicting complications of pancreatic surgery.

Keywords:
поджелудочная железа, резекция, осложнения, PREPARE, прогнозирование, pancreas, resection, complications, PREPARE, prognosis