Медицинская литература. Новинки

 

 

 

 

 

 

“Паттерновый подход”, или поиск новых шаблонов. Комментарии к статье “Изучение значимости тиреоглобулина в крови в качестве биомаркера при оценке тяжести йододефицитных состояний в Узбекистане”

Вы можете загрузить полный текст статьи в формате pdf

Наука никогда не остановится в своем поиске новых решений. Процесс исследования и прогнозирования научными теориями есть процесс выявления и управления паттернами - совокупностями повторяющихся шаблонов, устойчивыми комбинациями и последовательностями. На протяжении многих лет проблема йодного дефицита сохраняет свою значимость для мирового здравоохранения. Несмотря на все предпринимаемые меры по ликвидации данной катастрофы, в настоящее время оптимизировать ее диагностику и лечение не удается, таким образом, ранее опубликованная в журнале “Клиническая и экспериментальная тиреоидология” работа “Изучение значимости тиреоглобулина в крови в качестве биомаркера при оценке тяжести йододефицитных состояний в Узбекистане” является невероятно актуальной и, несомненно, требует детального разбора, чему и посвящена данная статья.

Ключевые слова:
йододефицитные заболевания, йод, дефицит, тиреоглобулин, iodine deficiency disorders, iodine, deficiency, thyroglobulin

Литература:
1.1. Iodine Global Network Iodine deficiency 2015. [Интернет] Доступно по ссылке URL: http://ign.org/p142000263.html. Accessed September 16, 2015.
2.2. Герасимов Г.А., Фадеев В.В., Свириденко Н.Ю., и др. Йододефицитные заболевания в России. Простое решение сложной проблемы. - М., 2002. - С. 19-65.
3.3. Zimmermann MB, Jooste PL, Pandav CS. Iodine-deficiency disorders. Lancet. 2008;372(9645):1251-1262. doi: 10.1016/S0140-6736(08)61005-3.
4.4. Zimmermann MB. Iodine deficiency. Endocr Rev. 2009;30(4): 376-408. doi: 10.1210/er.2009-0011.
5.5. World Health Organization, UNICEF, International Council for Control of Iodine Deficiency Disorders. Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers. 3rd ed. Geneva: World Health Organization; 2007.
6.6. World Health Organization, UNICEF, ICCIDD. Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers. Geneva: WHO, 2001.
7.7. Spencer CA, Wang CC. Thyroglobulin measurement. Techniques, clinical benefits, and pitfalls. Endocrinol Metab Clin North Am. 1995;24(4):841-863.
8.8. Zimmermann MB, Aeberli I, Andersson M, et al. Thyroglobulin is a sensitive measure of both deficient and excess iodine intakes in children and indicates no adverse effects on thyroid function in the UIC range of 100-299 mug/L: a UNICEF/ICCIDD study group report. J ClinEndocrinol Metab. 2013;98(3):1271-1280. doi: 10.1210/jc.2012-3952.
9.9. Zimmermann MB, Moretti D, Chaouki N, Torresani T. Development of a dried whole-blood spot thyroglobulin assay and its evaluation as an indicator of thyroid status in goitrous children receiving iodized salt. Am J Clin Nutr. 2003;77(6):1453-1458.
10.10. Zimmermann MB, de Benoist B, Corigliano S, et al. Assessment of iodine status using dried blood spot thyroglobulin: development of reference material and establishment of an international reference range in iodine-sufficient children. J Clin Endocrinol Metab. 2006;91(12):4881-4887.doi: 10.1210/jc.2006-1370.
11.11. Spencer CA. Challenges of serum thyroglobulin (Tg) measurement in the presence of Tg autoantibodies. J Clin Endocrinol Metab. 2004;89(8):3702-3704. doi: 10.1210/jc.2004-0986.
12.12. Spencer CA, Takeuchi M, Kazarosyan M, et al. Serum thyroglobulin autoantibodies: prevalence, influence on serum thyroglobulin measurement, and prognostic significance in patients with differentiated thyroid carcinoma. J Clin Endocrinol Metab. 1998;83(4): 1121-1127. doi: 10.1210/jcem.83.4.4683.
13.13. Netzel BC, Grant RP, Hoofnagle AN, et al. First steps toward harmonization of LC-MS/MS thyroglobulin assays. Clin Chem. 2016;62(1):297-299. doi: 10.1373/clinchem.2015.245266.
14.14. Zimmermann MB, Aeberli I, Andersson M, et al. Thyroglobulin is a sensitive measure of both deficient and excess iodine intakes in children and indicates no adverse effects on thyroid function in the UIC range of 100-299 mug/L: a UNICEF/ICCIDD study group report. J ClinEndocrinol Metab. 2013;98(3):1271-1280. doi: 10.1210/jc.2012-3952.
15.15. Spencer CA, Takeuchi M, Kazarosyan M, et al. Serum thyroglobulin autoantibodies: prevalence, influence on serum thyroglobulin measurement, and prognostic significance in patients with differentiated thyroid carcinoma. J Clin Endocrinol Metab. 1998;83(4): 1121-1127. doi: 10.1210/jcem.83.4.4683.
16.16. Spencer C, Petrovic I, Fatemi S, LoPresti J. Serum thyroglobulin (Tg) monitoring of patients with differentiated thyroid cancer using sensitive (second-generation) immunometric assays can be disrupted by false-negative and false-positive serum thyroglobulin autoantibody misclassifications. J Clin Endocrinol Metab. 2014; 99(12):4589-4599. doi: 10.1210/jc.2014-1203.
17.17. Pearce EN, Caldwell KL. Urinary iodine, thyroid function, and thyroglobulin as biomarkers of iodine status. Am J Clin Nutr. 2016;104 Suppl 3:898S-901S. doi: 10.3945/ajcn.115.110395.
18.18. Krejbjerg A, Bjergved L, Bulow Pedersen I, et al. Serum thyroglobulin as a biomarker of iodine deficiency in adult populations. Clin Endocrinol (Oxf). 2016;85(3):475-482. doi: 10.1111/cen.13037.

“Pattern approach” or search for new templates. Respond to the article “Evaluating of significance of thyroglobulin (Tg) level in blood as a biomarker of iodine deficiency disorders severity in Uzbekistan”

Science will never stop in its search for new solutions. The process of investigating and predicting by scientific theories - is the process of identifying and managing patterns (sets of repetitive models, stable combinations and sequences). Over the years, the problem of iodine deficiency remains important for global health. Despite all the measures have been taken to eliminate this disease, now it is not possible to optimize iodine deficiency diagnosis and treatment all over the world. So, previously published in Clinical and experimental thyroidology journal article “Evaluating of significance of thyroglobulin (Tg) level in blood as a biomarker of iodine deficiency disorders severity in Uzbekistan” is incredibly relevant and undoubtedly requires detailed analysis. The analysis and comments to provided research is the subject of current article.

Keywords:
йододефицитные заболевания, йод, дефицит, тиреоглобулин, iodine deficiency disorders, iodine, deficiency, thyroglobulin