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Nephrogenic fibrosing dermatosis (NFD) is a serious delayed adverse reaction at patients with final stage of renal failure or with hemodialysis. Therefore at high risk patients (renal function's lesion) application of magnetic resonance contrast agents (MRCA) for contrast enhancement is restricted to clinical indications. To defend a residual function of kidneys one recommends to use a dosage of gadolinium containing MRCA not more than 0,3 mmol/kg. To reduce a risk of development of NFD it's necessary to consider a way of MRI without contrast enhancement or application of an alternative method of imaging.
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