Медицинская литература. Новинки

 

 

 

 

 

 

Применение позитронной эмиссионной томографии в диагностике эпилепсии (обзор литературы)

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Цель исследования: анализ современного состояния лучевой диагностики эпилепсии с использованием позитронной эмиссионной томографии (ПЭТ) в сопоставлении с другими методами визуализации. В обзоре приводятся данные о роли различных медиаторных систем в патогенезе эпилепсии. Кроме того, детально рассмотрены возможности ПЭТ с 18F-фтордезоксиглюкозой и со специфическими радиофармпрепаратами для изучения различных нейротрансмиттерных систем в диагностике и оценке эффективности лечения височной и экстратемпоральной форм заболевания, резистентных к фармакологическому лечению.

Ключевые слова:
позитронная эмиссионная томография, эпилепсия, магнитно-резонансная томография, радиофармпрепарат, медиаторные системы.

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The Application of Positron Emission Tomography in Diagnosis of Epilepsy (Review)

The aim of the study is to analyze the current state of radiation diagnosis of epilepsy using positron emission tomography (PET) in comparison with other imaging methods. The review provides data on the role of various neurotransmitter systems in the pathogenesis of epilepsy. The possibility of PET with 18@Ffluorodeoxyglucose and radiopharmaceuticals for studying of the various neurotransmitter systems in the diagnosis and assessment of treatment efficacy of pharmacoresistant temporal and extratemporal epilepsy is discussed in detail.

Keywords:
positron emission tomography, epilepsy, magnetic resonance imaging, radiopharmaceutical, mediator systems.