Новости | Магазин | Журналы | Контакты | Правила | Доставка | |
Вход Регистрация |
Представленная статья отражает современный взгляд на возможности диагностического алгоритма рака влагалища (РВл) – редкого злокачественного новообразования женской репродуктивной системы. Алгоритм изложен в виде консенсуса ведущих специалистов по лучевой диагностике и онкогинекологов, занимающихся проблемами диагностики и лечения РВл. В статье изложены основные тренды по использованию методов лучевой диагностики, их роли и возможностях для стадирования РВл, планирования и оценки эффективности проводимой терапии, динамического наблюдения за пациентками, прошедшими специализированное противоопухолевое лечение.
Ключевые слова:
рак влагалища, МРТ, УЗИ, ПЭТ/КТ, sup>18/sup>F-фтордезоксиглюкоза, vaginal cancer, imaging, MRI, US, sup>18/sup>FDG, PET/CT
Литература:
1.Adams T.S., Rogers L.J., Cuello M.A. Cancer of the vagina: 2021 update. Int. J. Gynecol. Obstet. 2021; 155 (Suppl. 1): 19– 27. https://doi.org/10.1002/ijgo.13867
2.Sinno A.K., Saraiya M., Thompson T.D. et al. Human papillomavirus genotype prevalence in invasive vaginal cancer from a registry-based population. Obstet. Gynecol. 2014; 123 (4): 817–821. https://doi.org/10.1097/AOG.0000000000000171
3.Солопова А.Г., Москвичёва В.С., Блбулян Т.А., Шкода А.С., Макацария А.Д. Актуальные вопросы профилактики, диагностики и лечения рака вульвы и влагалища. Акушерство, гинекология и репродукция. 2018; 12 (4): 62–70. https://doi.org/10.17749/2313-7347.2018.12.4. 062-070
4.Guo L., Li C., Hua K. Occult vaginal cancer recurrence after hysterectomy: a case report and literature review. J. Int. Med. Res. 2020; 48 (12): 300060520973901. https://doi.org/10.1177/0300060520973901
5.Donati O.F., Lakhman Y., Sala E. et al. Role of preoperative MR imaging in the evaluation of patients with persistent or recurrent gynaecological malignancies before pelvic exenteration. Eur. Radiol. 2013; 23 (10): 2906–2915. https://doi.org/10.1007/s00330-013-2875-1
6.Каприн А.Д., Старинский В.В., Шахзадова А.О. Состояние онкологической помощи населению России в 2021 году. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ “НМИЦ радиологии” Минздрава России, 2022. 239 с. ISBN 978-5-85502-275-9
7.Клинические рекомендации, одобренные научным советом МЗ РФ. Злокачественные новообразования влагалища, 2020. https://www.cancer.org/research/cancer-factsstatistics/all-cancer-facts-figures/cancer-factsfigures-2020.html
8.American Cancer Society. Cancer Facts and Figures 2020. Atlanta, Ga: American Cancer Society; 2020. https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/cancer-facts-figures-2020.htm
9.Аксенова С.П., Солодкий В.А., Нуднов Н.В., Крейнина Ю.М., Котляров П.М., Сергеев Н.И., Ребрикова В.А., Мурзина А.А. Магнитно-резонансная томография в диагностике опухолевого поражения влагалища (по материалам методических рекомендаций). Вестник научного центра рентгенорадиологии. 2022; 22 (2). http://vestnik.rncrr.ru/vypusk/vypusk22/?ELEMENT_ID=71
10.Казумова А.А. Ультразвуковая диагностика опухолей влагалища и вульвы: Дис. … канд. мед. наук. Обнинск, 2010. 101 c.
11.Pozzati F., Moro F., Leombroni M. et al. Clinical and ultrasound characteristics of vaginal lesions. Int. J. Gynecol. Cancer. 2021; 31 (1): 45–51. https://doi.org/10.1136/ijgc-2020-001651
12.Fischerova D., Garganese G., Reina H. et al. Terms, definitions and measurements to describe sonographic features of lymph nodes: consensus opinion from the Vulvar International Tumor Analysis (VITA) group. Ultrasound Obstet. Gynecol. 2021; 57 (6): 861–879. https://doi.org/10.1002/uog.23617
13.Faria S., Devine C., Viswanathan C. et al. FDG-PET assessment of other gynecologic cancers. PET Clin. 2018; 13 (2): 203–223. https://doi.org/10.1016/j.cpet.2017.11.006
14.Robertson N.L., Hricak H., Sonoda Y. et al. The impact of FDG-PET/CT in the management of patients with vulvar and vaginal cancer. Gynecol. Oncol. 2016; 140 (3): 420–424. https://doi.org/10.1016/j.ygyno.2016.01.011
15.Gouveia P., Sa Pinto A., Violante L. et al. 18F-FDG PET/CT in Patients with Vulvar and Vaginal Cancer: A Preliminary Study of 20 Cases. Acta Med. Port. 2022; 35 (3): 170–175. https://doi.org/10.20344/amp.12510
16.Sadowski E.A., Pirasteh A., McMillan A.B. et al. PET/MR imaging in gynecologic cancer: tips for differentiating normal gynecologic anatomy and benign pathology versus cancer. Abdom. Radiol. (NY). 2022; 47 (9): 3189–3204. https://doi.org/10.1007/s00261-021-03264-9
17.Kilcoyne A., Gottumukkala R.V., Kang S.K. et al.; Expert Panel on GYN and OB Imaging. ACR Appropriateness Criteria® Staging and Follow-up of Primary Vaginal Cancer. J. Am. Coll. Radiol. 2021; 18: S442–S455. https://doi.org/10.1016/j.jacr.2021.08.011
18.Shetty A.S. Menias C.O. MR imaging of vulvar and vaginal cancer. Magn. Reson. Imaging Clin. N. Am. 2017; 25: 481–502. https://doi.org/10.1016/j.mric.2017.03.013
19.Ferreira D.M. Bezerra R.O.F. Ortega C.D. et al. Magnetic resonance imaging of the vagina: an overview for radiologists with emphasis on clinical decision making. Radiol. Bras. 2015; 48: 249–259. https://doi.org/10.1590/0100-3984.2013.1726
20.Parikh J.H., Barton D.P., Ind T.E., Sohaib S.A. MR imaging features of vaginal malignancies. Radiographics. 2008; 28 (1): 49–63; quiz 322. https://doi.org/10.1148/rg.281075065
21.Аксенова С.П., Нуднов Н.В., Солодкий В.А. Поиск оптимального МР-протокола для диагностики опухолевого поражения влагалища. Вестник рентгенологии и радиологии. 2022; 103 (4–6): 58–70. https://doi.org/10.20862/0042-4676-2022-103-4-6-58-70
22.Manganaro L., Lakhman Y., Bharwani N. et al. Staging, recurrence and follow-up of uterine cervical cancer using MRI: Updated Guidelines of the European Society of Urogenital Radiology after revised FIGO staging 2018. Eur. Radiol. 2021; 31 (10): 7802–7816. https://doi.org/10.1007/s00330-020-07632-9. Epub 2021 Apr 14. Erratum in: Eur Radiol. 2021 Jun 17.
23.Proscia N., Jaffe T.A., Neville A.M. et al. MRI of the pelvis in women: 3D versus 2D T2-weighted technique. Am. J. Roentgenol. 2010; 195 (1): 254–259. https://doi.org/10.2214/ajr.09.3226
24.Alt C.D., Bharwani N., Danza F.M. et al. ESUR Quick Guide to Female Pelvis Imaging. 2019; https://www.researchgate.net/publication/334725882_ESUR_Quick_Guide_to_Female_Pelvis_Imaging
25.Bhardwaj R., Boruah D.K., Gogoi B.B. et al. Added-Value of Diffusion-Weighted Imaging (DWI) and Dynamic Contrast-Enhanced (DCE-MRI) Magnetic Resonance Imaging in the Preoperative Assessment of Cervical Cancer. J. Obstet. Gynaecol. India. 2022; 72 (4): 330–340. https://doi.org/10.1007/s13224-021-01488-9
26.Chow L., Tsui B.Q., Bahrami S. et al. Gynecologic tumor board: a radiologist's guide to vulvar and vaginal malignancies. Abdom. Radiol. (NY). 2021; 46 (12): 5669–5686. https://doi.org/10.1007/s00261-021-03209-2
27.Lamoreaux W.T., Grigsby P.W., Dehdashti F. et al. FDG-PET evaluation of vaginal carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 2005; 62 (3): 733–737. https://doi.org/10.1016/j.ijrobp.2004.12.011
28.Brar H., May T., Tau N. et al. Detection of extra-regional tumour recurrence with 18F-FDG-PET/CT in patients with recurrent gynaecological malignancies being considered for radical salvage surgery. Clin. Radiol. 2017; 72 (4): 302–306. https://doi.org/10.1016/j.crad.2016.12.009
29.ACR–SABI–SAR–SPR Practice parameter for the performance of computed tomography (CT) of the abdomen and computed tomography (CT) of the pelvis. Practice parameter. CT abdomen CT pelvis. revised 2021 (resolution 46)
30.Burton C.S., Frey K., Fahey F. et al. Fetal Dose from PET and CT in Pregnant Patients. J. Nucl. Med. 2023; 64 (2): 312–319. https://doi.org/10.2967/jnumed.122.263959
31.NCCN Clinical Practice Guidelines in Oncology. Cervical cancer. Version 1.2020. Available at. https://www.nccn.org/professionals/physician_gls/pdf/cervical.pdf
32.Nout R., Calaminus G., Planchamp F. et al. ESTRO/ESGO/ SIOPe guidelines for the management of patients with vaginal cancer. Radiother Oncol. 2023 Sep;186:109662. https://doi.org/10.1016/j.radonc.2023.109662
33.Friedman S.N., Itani M., Dehdashti F. PET Imaging for Gynecologic Malignancies. Radiol. Clin. N. Am. 2021; 59 (5): 813–833. https://doi.org/10.1016/j.rcl.2021.05.011
34.Gardner C.S., Sunil J., Klopp A.H. et al. Primary vaginal cancer: role of MRI in diagnosis, staging and treatment. Br. J. Radiol. 2015; 88 (1052): 20150033. https://doi.org/10.1259/bjr.20150033
35.Коржевская Е.В., Кузнецов В.В., Грицай А.Н. Злокачественные опухоли влагалища. Клиническая онкогинекология: Руководство для врачей / Под ред. В.П. Козаченко. 2-е изд., перераб. и доп. М.: Издательство Бином, 2016: 97–108.
36.Choi H.J., Ju W., Myung S.K., Kim Y. Diagnostic performance of computer tomography, magnetic resonance imaging, and positron emission tomography or positron emission tomography/computer tomography for detection of metastatic lymph nodes in patients with cervical cancer: meta-analysis. Cancer Sci. 2010; 101 (6): 1471–1479. https://doi.org/10.1111/j.1349-7006.2010.01532.x
37.Albuquerque K.S., Zoghbi K.K., Gomes N.B.N. et al. Vaginal cancer: Why should we care? Anatomy, staging and in-depth imaging-based review of vaginal malignancies focusing on MRI and PET/CT. Clin. Imaging. 2022; 84: 65–78. https://doi.org/10.1016/j.clinimag.2022.01.009
38.Garganese G., Collarino A., Fragomeni S.M. et al. Groin sentinel node biopsy and 18F-FDG PET/CT-supported preoperative lymph node assessment in cN0 patients with vulvar cancer currently unfit for minimally invasive inguinal surgery: The GroSNaPET study. Eur. J. Surg. Oncol. 2017; 43 (9): 1776-1783. https://doi.org/10.1016/j.ejso.2017.06.018
The article offers the latest view on possibilities of diagnostic algorithm to identify vaginal cancer (VC), rare tumor of the woman’s reproductive system. The algorithm is described as a consensus of leading expert in imaging diagnostics, as well as oncogynecologysts, investigating diagnostic challenges and vaginal cancer therapies. The article sets forth the principal trends in using imaging methods, their role and possibilities for staging VC, planning and assessing the efficacy of applied therapy, on-going surveillance over patients, who have undergone specialized anti-cancer treatment
Keywords:
рак влагалища, МРТ, УЗИ, ПЭТ/КТ, sup>18/sup>F-фтордезоксиглюкоза, vaginal cancer, imaging, MRI, US, sup>18/sup>FDG, PET/CT