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Представлен методический подход при выполнении магнитнорезонансной томографии для диагностики стадии местной распространенности рака прямой кишки. Магнитно-резонансная томография является эффективным методом в точной предоперационной диагностике стадии рака прямой кишки. Для обеспечения стандартизации визуализации и интерпретации результатов для радиологов, участвовавших в европейском исследовании изучения магнитнорезонансной визуализации рака прямой кишки (Magnetic Resonance Imaging and Rectal Cancer European Equivalence Study(MERCURY), были проведены семинары. В статье описаны процессы получения информации, приведены примеры томограмм и их интерпретаций, чтобы обеспечить единый методический подход к оценке результатов исследования.
Ключевые слова:
магнитно-резонансная томография, рак прямой кишки.
Литература:
1. Blomqvist L., Rubio C., Holm T. et al. Rectal adenocarci
noma: assessment of tumour involvement of the lateral
resection margin by MRI of resected specimen. Br J
Radiol. 1999; 72: 18 23.
2. Brown G., Davies S., Williams G.T. et al. Effectiveness of
preoperative staging in rectal cancer: digital rectal examination, endoluminal ultrasound or magnetic resonance
imaging? Br J Cancer2004; 91: 2329.
3. Brown G., Kirkham A., Williams G.T. et al. Highresolution
MRI of the anatomy important in total mesorectal excision
of the rectum. AJR 2004; 182: 431439.
4. Brown G., Radcliffe A.G., Newcombe R.G. et al.
Preoperative assessment of prognostic factors in rectal
cancer using highresolution magnetic resonance imaging. Br J Surg 2003; 90: 355364.
5. MERCURY Study Group. Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative
resection of rectal cancer: prospective observational
study. BMJ 2006; 333: 779. Epub 2006 Sep 19.
6. Burton S., Brown G., Daniels I.R. et al. MRI directed multidisciplinary team preoperative treatment strategy: the way
to eliminate positive circumferential margins? Br J Cancer
2006; 94: 351357.
7. Glimelius B., Oliveira J. Rectal cancer: ESMO clinical recommendations for diagnosis, treatment and followup.
Ann Oncol 2008; 9[suppl 2]: ii31 ii32.
8. The Association of Coloproctography of Great Britain and
Ireland. Guidelines for the management of colorectal cancer. London, UK: ACPGBI, 2007.
9. Brown G., Daniels I.R., Richardson C. et al. Techniques
and troubleshooting in high spatial resolution thin slice
MRI for rectal cancer. Br J Radiol 2005; 78: 245251.
10. Okizuka H., Sugimura K., Yoshizako T. et al. Rectal carcinoma: prospective comparison of conventional and
gadopentetate dimeglumine enhanced fatsuppressed
MR imaging. J Magn Reson Imaging 1996; 6: 465471.
11. Vliegen R.F., Beets G.L., von Meyenfeldt M.F. et al. Rectal
cancer: MR imaging in local stagingis gadoliniumbased
contrast material helpful? Radiology 2005; 234: 179188.
12. Koh D.M., Brown G., Temple L., et al. Distribution of
mesorectal lymph nodes in rectal cancer: in vivo MR imaging compared with histopathological examination initial
observations. Eur Radiol 2005; 15: 16501657.
13. Zand K.R., Reinhold C., Haider M.A. et al. Artifacts and pitfalls in MR imaging of the pelvis. J Magn Reson Imaging
2007; 26: 480497.
14. Salerno G., Daniels I.R., Moran B.J. et al. Clarifying margins in the multidisciplinary management of rectal cancer:
the MERCURY experience. Clin Radiol 2006; 61: 916923
15. Shepherd N.A., Baxter K.J., Love S.B. Influence of local
peritoneal involvement on pelvic recurrence and progno
sis in rectal cancer. J Clin Pathol 1995; 48: 849855.
16. Smith N.J., Barbachano Y., Norman A.R. et al. Prognostic
significance of magnetic resonance imagingdetected
extramural vascular invasion in rectal cancer. Br J Surg
2008; 95: 229236.
17. Brown G., Richards C.J., Bourne M.W. et al. Morphologic
predictors of lymph node status in rectal cancer with use
of highspatialresolution MR imaging with histopathologic comparison. Radiology 2003; 227: 371377.
18. Kim J.H., Beets G.L., Kim M.J. et al. Highresolution MR
imaging for nodal staging in rectal cancer: are there any
criteria in addition to the size? Eur J Radiol 2004; 52: 78
83.
19. Koh D.M., Brown G., Temple L. et al. Rectal cancer:
mesorectal lymph nodes at MR imaging with USPIO versus
histopathologic findings initial observations. Radiology
2004; 231: 9199.
20. Jass J.R. Lymphocytic infiltration and survival in rectal
cancer. J Clin Pathol 1986; 39: 585589.21. Sugihara K., Kobayashi H., Kato T. et al. Indication and
benefit of pelvic sidewall dissection for rectal cancer. Dis
Colon Rectum 2006; 49: 16631672.
22. Dworak O., Keilholz L., Hoffmann A. Pathological features
of rectal cancer after preoperative radiochemotherapy. Int
J Colorectal Dis 1997; 12: 1923.
23. Bouzourene H., Bosman F.T., Seelentag W. et al.
Importance of tumor regression assessment in predicting
the outcome in patients with locally advanced rectal carcinoma who are treated with preoperative radiotherapy.
Cancer 2002; 94: 11211130.
24. Cohen A.M., Wood W.C., Gunderson L.L., Shinnar M.
Pathological studies in rectal cancer. Cancer 1980; 45:
29652968.
25. Bjerkeset T., Morild I., Mork S., Soreide O. Tumor characteristics in colorectal cancer and their relationship to treatment and prognosis. Dis Colon Rectum 1987; 30: 934
938.
26. Michelassi F., Vannucci L., Montag Aю et al. Importance of
tumor morphology for the long term prognosis of rectal
adenocarcinoma. Am Surg 1988; 54: 376379.
27. Grinnell R.S. The grading and prognosis of carcinoma of
the colon and rectum. Ann Surg 1939; 109: 500533.
28. Spratt J.A., Spjut H.J. Prevalence and prognosis of carcinoma of the colon and rectum. Cancer 1967; 20: 1976
1985.
29. Halvorsen T.B., Seim E. Association between invasiveness, inflammatory reaction, desmoplasia and survival in
colorectal cancer. J Clin Pathol 1989; 42: 162166.
30. Hughes T.G., Jenevein E.P., Poulos E. Intramural spread of
colon carcinoma: a pathologic study. Am J Surg 1983;
146: 697699.
31. Madsen P.M., Christiansen J. Distal intramural spread of
rectal carcinomas. Dis Colon Rectum 1986; 29: 279282.
32. Andreola S., Leo E., Belli F. et al. Distal intramural spread
in adenocarcinoma of the lower third of the rectum treated
with total rectal resection and coloanal anastomosis. Dis
Colon Rectum 1997; 40: 2529.
33. Sidoni A., Bufalari A., Alberti P.F.. Distal intramural spread
in colorectal cancer: a reappraisal of the extent of distal
clearance in fifty cases. Tumori 1991; 77: 514517.
34. Kim M.J., Park J.S., Park S.I. et al. Accuracy in differentiation of mucinous and nonmucinous rectal carcinoma on
MR imaging. J Comput Assist Tomogr 2003; 27: 48 55.
35. Sobin L., Wittekind C. TNM classification of malignant
tumors, 5th ed. New York, NY: Wiley, 1997: 227.
36. Kapiteijn E., Marijnen C.A., Nagtegaal I.D. et al.
Preoperative radiotherapy combined with total mesorectal
excision for resectable rectal cancer. N Engl J Med 2001;
345: 638646.
37. Laghi A., Ferri M., Catalano C. et al. Local staging of rectal
cancer with MRI using a phased array body coil. Abdom
Imaging 2002; 27: 425431.
38. BeetsTan R.G., Beets G.L, Vliegen R.F. et al. Accuracy of
magnetic resonance imaging in prediction of tumourfree
resection margin in rectal cancer surgery. Lancet 2001;
357: 497504
39. Sauer R., Becker H., Hohenberger W. et al. Preoperative
versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004; 351: 17311740.
40. Brown G., Richards C.J., Newcombe R.G. et al. Rectal
carcinoma: thinsection MR imaging for staging in 28
patients. Radiology 1999; 211: 215222.
41. Chau I., Brown G., Cunningham D. et al. Neoadjuvant
capecitabine and oxaliplatin followed by synchronous
chemoradiation and total mesorectal excision in magnetic
resonance imagingdefined poorrisk rectal cancer. J Clin
Oncol 2006; 24: 668674.
42. Koeberle D., Burkhard R., von Moos R. et al. Phase II
study of capecitabine and oxaliplatin given prior to and
concurrently with preoperative pelvic radiotherapy in
patients with locally advanced rectal cancer. Br J Cancer
2008; 98: 12041209.
43. Dahlberg M., Glimelius B., Graf W., Pahlman L.
Preoperative irradiation affects functional results after
surgery for rectal cancer: results from a randomized study.
Dis Colon Rectum 1998; 41: 543 549; discussion 549551.
44. Wong R.K., Tandan V., De Silva S., Figueredo A. Pre-operative radiotherapy and curative surgery for the management of localized rectal carcinoma. Cochrane Database
Syst Rev 2007 Apr; 18;(2): CD002102.
45. Cawthorn S.J., Gibbs N.M., Marks C.G. Clearance technique for the detection of lymph nodes in colorectal cancer. Br J Surg 1986; 73: 5860.
46. Jass J.R., Love S.B. Prognostic value of direct spread in
Dukes' C cases of rectal cancer. Dis Colon Rectum 1989;
32: 477480.
47. Adam I.J., Mohamdee M.O., Martin I.G. et al. Role of circumferential margin involvement in the local recurrence of
rectal cancer. Lancet 1994; 344: 707711.
48. Hall N.R., Finan P.J., alJaberi T. et al. Circumferential margin involvement after mesorectal excision of rectal cancer
with curative intent: predictor of survival but not local
recurrence? Dis Colon Rectum 1998; 41: 979983.
49. Birbeck K.F., Macklin C.P., Tiffin N.J. et al. Rates of circumferential resection margin involvement vary between
surgeons and predict outcomes in rectal cancer surgery.
Ann Surg 2002; 235: 449457.
50. Marr R., Birbeck K., Garvican J. et al. The modern
abdominoperineal excision: the next challenge after total
mesorectal excision. Ann Surg 2005; 242: 7482.
51. MERCURY Study Group. Extramural depth of tumor invasion at thinsection MR in patients with rectal cancer:
results of the MERCURY study. Radiology 2007; 243: 132139.
52. Dehni N., McFadden N., McNamara D.A. et al. Oncologic
results following abdominoperineal resection for adenocarcinoma of the low rectum. Dis Colon Rectum 2003; 46:
867874; discussion 874.
53. Heald R.J., Smedh R.K., Kald A. et al. Abdominoperineal
excision of the rectum: an endangered operation. Norman
Nigro Lectureship. Dis Colon Rectum 1997; 40: 747751.
54. Salerno G., Chau I., Tait D. et al. Interpretation of
postchemoradiation MRI compared with histopathology
in low rectal cancer. Colorectal Disease 2007; 9 [1suppl]:
9293.
The article deals with the methodic of MRI for diagnos tics of local extension of a rectal cancer. MRI is an effective method for precise preoperative staging of a rectal cancer. For unification of the method and evaluation of the results by radiologists, involved into the European Trial (Magnetic Resonance Imaging and Rectal Cancer European Equivalence Study MERCURY) the workshops have been conducted. The methodic of examination's performing; examples of images and resolutions are suggested.
Keywords:
magnetic resonance images, rectal cancer.