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Представлен анализ итогов трех наиболее важных международных согласительных конференций (2008, 2014, 2017), посвященных освоению, распространению, оценке возможностей и безопасности лапароскопической резекции печени. Анализ мирового опыта продемонстрировал медленное, но уверенное повсеместное распространение новой технологии. Доказано, что ближайшие результаты лапароскопической резекции превосходят результаты открытой резекции, а отдаленные не отличаются при наиболее распространенных доброкачественных и злокачественных новообразованиях при условии отбора пациентов. В отличие от лапароскопической хирургии других органов брюшной полости, многие вопросы, касающиеся технологии, безопасности и воспроизводимости операции, не получили окончательного решения в силу медленного набора данных и других объективных препятствий, связанных прежде всего со сложностью хирургической анатомии печени. Существенным достижением работы экспертов следует считать четкое определение стратегии освоения технологии лапароскопической резекции, а также отбора пациентов, позволяющих избежать серьезных ошибок и дискредитации метода. Все конференции оставались в русле первоначально наметившихся тенденций, добавляя более доказательные исследования для подтверждения и детализации возможностей технологии. Сохраняется дефицит проспективных рандомизированных исследований и крупных национальных и международных регистров. Дальнейший анализ опыта позволит скорректировать полученные ранее результаты, более четко обозначить роль и место лапароскопической резекции печени в арсенале современной хирургической гепатологии.
Ключевые слова:
печень, лапароскопическая резекция, рекомендации, консенсус, liver, laparoscopic resection, recommendations, consensus
Литература:
1.Ефанов М.Г., Алиханов Р.Б., Цвиркун В.В., Казаков И.В., Ким П.П., Ванькович А.Н., Грендаль К.В., Заманов Э.Н. Ближайшие результаты минимально инвазивных и открытых резекций печени по поводу колоректального рака. Опыт специализированного центра. Альманах клинической медицины. 2018; 46 (6): 584-591. https://doi.org/10.18786/2072-0505-2018-46-5.
2.Buel l J.F., Cherqui D., Geller D.A., O’Rourke N., Iannitti D., Dagher I., Koffron A.J., Thomas M., Gayet B., Han H.S., Wakabayashi G., Belli G., Kaneko H., Ker C.G., Scatton O., Laurent A., Abdalla E.K., Chaudhury P., Dutson E., Gamblin C., D''Angelica M., Nagorney D., Testa G., Labow D., Manas D., Poon R.T., Nelson H., Martin R., Clary B., Pinson W.C., Martinie J., Vauthey J.N., Goldstein R., Roayaie S., Barlet D., Espat J., Abecassis M., Rees M., Fong Y., McMasters K.M., Broelsch C., Busuttil R., Belghiti J., Strasberg S., Chari R.S.; World Consensus Conference on Laparoscopic Surgery. The international position on laparoscopic liver surgery: the Louisville Statement, 2008. Ann. Surg. 2009; 250 (5): 825-830. https://doi.org/10.1097/sla.0b013e3181b3b2d8.
3.Hibi T., Cherqui D., Geller D.A., Itano O., Kitagawa Y., Wakabayashi G. International Survey on Technical Aspects of Laparoscopic Liver Resection: a web-based study on the global diffusion of laparoscopic liver surgery prior to the 2nd International Consensus Conference on Laparoscopic Liver Resection in Iwate, Japan. J. Hepatobiliary Pancreat. Sci. 2014; 21 (10): 737-744. https://doi.org/10.1002/jhbp.141.
4.Hibi T., Cherqui D., Geller D.A., Itano O., Kitagawa Y., Wakabayashi G. Expanding indications and regional diversity in laparoscopic liver resection unveiled by the International Survey on Technical Aspects of Laparoscopic Liver Resection (INSTALL) study. Surg. Endosc. 2016; 30 (7): 2975-2983. https://doi.org/10.1007/s00464-015-4586-y.
5.Ban D., Tanabe M., Ito H., Otsuka Y., Nitta H., Abe Y., Hasegawa Y., Katagiri T., Takagi C., Itano O., Kaneko H., Wakabayashi G. A novel difficulty scoring system for laparoscopic liver resection. J. Hepatobiliary Pancreat. Sci. 2014; 21 (10): 745-753. https://doi.org/10.1002/jhbp.166.
6.Dagher I., Gayet B., Tzanis D., Hadrien T., Fuks D., Soubrane O., Han H., Kim K., Cherqui D., O’Rourke N., Troisi R.I., Aldrighetti L., Bjorn E., AbuHilal M., Belli G., Kaneko H., Jarnagin W.R., Lin C., Pekolj J., Buell J.F., Wakabayashi G. International experience for laparoscopic major liver resection. J. Hepatobiliary Pancreat. Sci. 2014; 21 (10): 732-736. https://doi.org/10.1002/jhbp.140.
7.Wakabayashi G., Cherqui D., Geller D.A., Han H., Kaneko H., Buell J.F. Laparoscopic hepatectomy is theoretically better than open hepatectomy: preparing for the 2nd International Consensus Conference on Laparoscopic Liver Resection. J. Hepatobiliary Pancreat. Sci. 2014; 21 (10): 723-731. https://doi.org/10.1002/jhbp.139.
8.Wakabayashi G. What has changed after the Morioka consensus conference 2014 on laparoscopic liver resection? HepatoBiliary Surg. Nutr. 2016; 5 (4): 281-289. https://doi.org/10.21037/hbsn.2016.03.03.
9.Ban D., Kudo A., Ito H., Mitsunori Y., Matsumura1 S., Aihara A., Ochiai T., Tanaka S., Tanabe M., Itano O., Kaneko H., Wakabayashi G. The difficulty of laparoscopic liver resection. Updates Surg. 2015; 67 (2): 123-128. https://doi.org/10.1007/s13304-015-0302-7.
10.Abu Hilal M., Aldrighetti L., Dagher I., Edwin B., Troisi R.I., Alikhanov R., Aroori S., Belli G., Besselink M., Briceno J., Gayet B., D''Hondt M., Lesurtel M., Menon K., Lodge P., Rotellar F., Santoyo J., Scatton O., Soubrane O., Sutcliffe R., Van Dam R., White S., Halls M.C., Cipriani F., Van der Poel M., Ciria R., Barkhatov L., Gomez-Luque Y., Ocana-Garcia S., Cook A., Buell J., Clavien P.A., Dervenis C., Fusai G., Geller D., Lang H., Primrose J., Taylor M., Van Gulik T., Wakabayashi G., Asbun H., Cherqui D. The Southampton Consensus Guidelines for laparoscopic liver surgery: from indication to implementation. Ann. Surg. 2018; 268 (1): 11-18. https://doi.org/10.1097/SLA.0000000000002524.
11.Dalkey N.C., Helmer O. An experimental application of the Delphi method to the use of experts. Manage Sci. 1963; 9 (3): 458-467. https://doi.org/10.1287/mnsc.9.3.458.
12.Luo L.X., Yu Z.Y., Bai Y.N. Laparoscopic hepatectomy for liver metastases from colorectal cancer: a meta-analysis. J. Laparoendosc. Adv. Surg. Techn. 2014; 24 (4): 213-222. https://doi.org/10.1089/lap.2013.0399.
13.Clinical trial.gov. Trial Registry. U.S. National Institutes of Health. Available at: https://clinicaltrials.gov.
14.Cipriani F., Rawashdeh M., Stanton L., Armstrong T., Takhar A., Pearce N.W., Primrose J., Abu Hilal M. Propensity score-based analysis of outcomes of laparoscopic versus open liver resection for colorectal metastases. Br. J. Surg. 2016; 103 (11): 1504-1512. https://doi.org/10.1002/bjs.10211.
15.Mart??nez-Cecilia F., Cipriani F., Shelat V., Ratti F., Tranchart H., Barkhatov L., Tomassini F., Montalti R., Halls M., Troisi R.I., Dagher I., Aldrighetti L., Edwin B., Abu Hilal M. Laparoscopic versus open liver resection for colorectal metastases in elderly and octogenarian patients. Ann. Surg. 2017; 265 (6): 1192-1200. https://doi.org/10.1097/SLA.0000000000002147.
16.Montalti R., Tomassini F., Laurent S., Smeets P., De Man M., Geboes K., Libbrecht L.J., Troisi R.I. Impact of surgical margins on overall and recurrence-free survival in parenchymal-sparing laparoscopic liver resections of colorectal metastases. Surg. Endosc. 2015; 29 (9): 2736-2747. https://doi.org/10.1007/s00464-014-3999-3.
17.Croome K.P., Yamashita M.H. Laparoscopic vs open hepatic resection for benign and malignant tumours: an updated metaanalysis. Arch. Surg. 2010; 145 (11): 1109-1118. https://doi.org/10.1001/archsurg.2010.227.
18.Xiong J.J., Altaf K., Javed M.A., Huang W., Mukherjee R., Mai G., Sutton R., Liu X.B., Hu W.M. Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma. World J. Gastroenterol. 2012; 18 (45): 6657-6668. https://doi.org/10.3748/wjg.v18.i45.6657.
19.Morise Z., Ciria R., Cherqui D., Chen K.H., Belli G., Wakabayashi G. Can we expand the indications for laparoscopic liver resection? A systematic review and meta-analysis of laparoscopic liver resection for patients with hepatocellular carcinoma and chronic liver disease. J. Hepatobiliary Pancreat. Sci. 2015; 22 (5): 342-352. https://doi.org/10.1002/jhbp.215.
20.Samstein B., Griesemer A., Cherqui D., Mansour T., Pisa J., Yegiants A., Fox A.N., Guarder J.V., Kato T., Halazun K.J., Emond J. Fully laparoscopic left-sided donorhepatectomy is safe and associated with shorter hospital stay and earlier returnto work: a comparative study. Liver Transpl. 2015; 21 (6): 768-773. https://doi.org/10.1002/lt.24116.
21.Cauchy F., Fuks D., Nomi T., Dokmak S., Scatton O., Schwarz L., Barbier L., Belghiti J., Soubrane O., Gayet B. Benefits of laparoscopy in elderly patients requiring major liver resection. J. Am. Coll. Surg. 2016; 222 (2): 174-184. https://doi.org/10.1016/j.jamcollsurg.2015.11.006.
22.Fuks D., Nomi T., Ogiso S., Gelli M., Velayutham V., Conrad C., Louvet C., Gayet B. Laparoscopic two-stage hepatectomy for bilobar colorectal liver metastases. Br. J. Surg. 2015; 102 (13): 1684-169. https://doi.org/10.1002/bjs.9945.
23.Ai J.H., Li J.W., Chen J., Bie P., Wang S.G., Zheng S.G. Feasibility and safety of laparoscopic liver resection for hepatocellular carcinoma with a tumor size of 5-10 cm. PLoS One. 2013; 8 (8): 723-728. https://doi.org/10.1371/journal.pone.0072328.
24.Yoon Y.S., Han H.S., Cho J.Y., Kim J.H., Kwon Y. Laparoscopic liver resection for centrally located tumors close to the hilum, major hepatic veins, or inferior vena cava. Surgery. 2013; 153 (4): 502-509. https://doi.org/10.1016/j.surg.2012.10.004.
25.Ciria R., Cherqui D., Geller A., Briceno J., Wakabayashi G. Comparative short-term benefits of laparoscopic liver resection: 9000 cases and climbing. Ann. Surg. 2016; 263 (4): 761-777. https://doi.org/10.1097/SLA.0000000000001413.
26.Lee W., Han H.S., Yoon Y.S., Cho J.Y., Choi Y., Shin H.K., Jang J.Y., Choi H., Jang J.S., Kwon S.U. Comparison of laparoscopic liver resection for hepatocellular carcinoma located in the posterosuperior segments or antero-lateral segments: a case-matched analysis. Surgery. 2016; 160 (5): 1219-1226. https://doi.org/10.1016/j.surg.2016.05.009.
27.Hasegawa Y., Koffron A.J., Buell J.F., Wakabayashi G. Approaches to laparoscopic liver resection: a meta-analysis of the role of hand-assisted laparoscopic surgery and the hybrid technique. J. Hepatobiliary Pancreat. Sci. 2015; 22 (5): 335-341. https://doi.org/10.1002/jhbp.214.
28.Qiu J., Chen S., Chengyou D. A systematic review of roboticassisted liver resection and meta-analysis of robotic versus laparoscopic hepatectomy for hepatic neoplasms. Surg. Endosc. 2016; 30 (3): 862-875. https://doi.org/10.1007/s00464-015-4306-7.
29.Vigano`L., Ferrero A., Amisano M., Russolillo N., Capussotti L. Comparison of laparoscopic and open intraoperative ultrasonography for staging liver tumours. Br. J. Surg. 2013; 100 (4): 535-542. https://doi.org/10.1002/bjs.9025.
30.Zhang Y., Yang H., Deng X., Chen Y., Zhu S., Kai C. Intermittent Pringle’s maneuver versus continuous hemihepatic vascular inflow occlusion using extra-glissonian approach in laparoscopic liver resection. Surg. Endosc. 2016; 30 (3): 961-970. https://doi.org/10.1007/s00464-015-4276-9.
31.Cauchy F., Fuks D., Nomi T., Schwarz L., Barbier L., Dokmak S., Scatton O., Belghiti J., Soubrane O., Gayet B. Risk factors and consequences of conversion in laparoscopic major liver resection. Br. J. Surg. 2015; 102 (7): 785-795. https://doi.org/10.1002/bjs.9806.
32.Goh B.K., Chan C.Y., Wong J.S., Lee S.Y., Lee V.T., Cheow P.C., Chow P.K., Ooi L.L., Chung A.Y. Factors associated with and the outcomes of open conversion after laparoscopic minor hepatectomy: initial experience at a single instituation. Surg. Endosc. 2015; 29 (9): 2636-2642. https://doi.org/10.1007/s00464-014-3981-0.
The article presents an analysis of the results of the three most important international consensus conferences on the development, dissemination, assessment of the efficacy and safety of laparoscopic liver resection (2008, 2014 and 2017). An analysis of world experience has demonstrated the slow but steady diffusion of the new technology. It is proved that the immediate outcomes of laparoscopic liver resection are superior to those for open resections, and the long-term results do not differ in the treatment of the most common oncological and benign liver tumors in selected patients. Unlike laparoscopic surgery of other organs of the abdominal cavity, many issues regarding the technology, safety and reproducibility of the operation did not receive a final solution due to the slower data set and other objective obstacles associated primarily with the complexity of the surgical anatomy of the liver. In this regard, a clear achievement of the expert’s work should be considered a clear definition of the strategy for mastering the technology of laparoscopic liver resection, as well as selection of patients to avoid serious errors and discrediting the method. All conferences remained in line with the initially emerging trends, adding more evidence-based research to confirm and refine the capabilities of the technology. There is still a shortage of prospective randomized trials and large national and international registries. Further analysis of experience in this direction will allow us to correct the previously obtained data and more clearly indicate the role and place of laparoscopic liver resection in the arsenal of methods of modern surgical hepatology.
Keywords:
печень, лапароскопическая резекция, рекомендации, консенсус, liver, laparoscopic resection, recommendations, consensus