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Обзор литературы демонстрирует необходимость дифференцированного подхода к нутритивной поддержке больных, оперированных на органах гепатопанкреатодуоденальной зоны. Представлены сведения о практике проведения нутритивной поддержки больных этой категории. Подчеркнута необходимость оценки риска нутритивной недостаточности до хирургического вмешательства. Коррекцию пищевого статуса следует основывать на потребности в белке и энергии пациента с учетом сопутствующих заболеваний. Методом выбора являются препараты для сипинга. В послеоперационном периоде предпочтение следует отдавать энтеральному питанию. Активно обсуждают вид нутритивной поддержки пациентов, перенесших панкреатодуоденальную резекцию, запланировано рандомизированное клиническое исследование для оценки эффективности энтерального и парентерального питания. Нутритивная поддержка, являясь составной частью программы ускоренного выздоровления, позволяет оптимизировать результаты лечения пациентов, перенесших вмешательства на органах гепатопанкреатодуоденальной зоны. Обязательной является оценка нутритивного статуса больного до операции. Периоперационная коррекция пищевого статуса подразумевает преемственность и мультидисциплинарный подход.
Ключевые слова:
нутритивная поддержка, гепатопанкреатобилиарная хирургия, сипинг, энтеральное питание
Литература:
1. Затевахин, И. И., Пасечник И.Н. Программа ускоренного выздоровления в хирургии (fast Trak) внедрена. Что дальше? // Вестник хирургии им. И.И. Грекова. - 2018. - Т. 177. - № 3. - С. 70-75. - https://doi.org/10.24884/0042-4625-2018-177-3-70-75./ Zatevachin I.I., Pasechnik I.N. THE PROGRAM OF ACCELERATED RECOVERY IN SURGERY (FAST TRAK) HAS BEEN INTRODUCED. WGAT’S THE NEXT? Grekov's Bulletin of Surgery. 2018;177(3):70-75. (In Russ.)
2. Программа ускоренного выздоровления хирургических больных : Fast track. Коллективная монография. Под ред. Затевахина И.И., Лядова К.В., Пасечника И.Н. - Москва : Общество с ограниченной ответственностью Издательская группа ''ГЭОТАР-Медиа'', 2017. - 208 с. / The program of accelerated recovery of surgical patients: Fast track. Collective monograph. GEOTAR_MED, 2017. 208 p. (In Russian).
3. Gilliland T.M, Villafane-Ferriol N., Shah K.P. et al Nutritional and Metabolic Derangements in Pancreatic Cancer and Pancreatic Resection. Nutrients. 2017;9(3):243. https://doi.org/10.3390/nu9030243
4. La Torre M., Ziparo V., Nigri G. et al. Malnutrition and pancreatic surgery: prevalence and outcomes. J Surg Oncol 2013;107(7):702-8. https://doi.org/10.1002/jso.23304.
5. El Amrani M.,Vermersch M., Fulbert M. et al. Impact of sarcopenia on outcomes of patients undergoing pancreatectomy: A retrospective analysis of 107 patients. Medicine (Baltimore). 2018;97(39):e12076. https://doi.org/10.1097/MD.0000000000012076.
6. Joliat G-R., Kobayashi K., Hasegawa K. et al. Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations 2022. World J Surg. 2022. https://doi.org/10.1007/s00268-022-06732-5.
7. Melloul E., Lassen K., Roulin D. et al. Guidelines for Perioperative Care for Pancreatoduodenectomy: Enhanced Recovery After Surgery (ERAS) Recommendations 2019. World J Surg. 2020;44(7):2056-2084. https://doi.org/10.1007/s00268-020-05462-w.
8. Chen L., Chen X., Li G. Nutritional management after hepatopancreatobiliary surgery. Hepatobiliary Surg Nutr. 2021;10(2):273-275. https://doi.org/10.21037/hbsn-2021-10.
9. Nagata S., Maeda S., Nagamatsu S. et al. Prognostic Nutritional Index Considering Resection Range Is Useful for Predicting Postoperative Morbidity of Hepatectomy. J Gastrointest Surg. 2021;25(11):2788-2795. https://doi.org/10.1007/s11605-020-04893-z.
10. Jiang P., Li X. 1, Wang S., Liu Y. Prognostic Significance of PNI in Patients With Pancreatic Head Cancer Undergoing Laparoscopic Pancreaticoduodenectomy. Front Surg. 2022;9:897033. https://doi.org/10.3389/fsurg.2022.897033.
11. Zhao P., Wu Z., Wang Z. et al. Prognostic role of the prognostic nutritional index in patients with pancreatic cancer who underwent curative resection without preoperative neoadjuvant treatment: A systematic review and meta-analysis. Front Surg. 2022;9:992641. https://doi.org/10.3389/fsurg.2022.992641.
12. Kim E., Kang J.S., Han Y. et al. Influence of preoperative nutritional status on clinical outcomes after pancreatoduodenectomy. HPB (Oxford) 2018;20(11):1051-1061. https://doi.org/10.1016/j.hpb.2018.05.004.
13. Weimann A., Braga M., Carli F. et al. ESPEN practical guideline: Clinical nutrition in surgery. Clin Nutr. 2021;40(7):4745-4761. https://doi.org/10.1016/j.clnu.2021.03.031.
14. Muscaritoli M., Arends J., Bachmann P. ESPEN practical guideline: Clinical Nutrition in cancer. Clin Nutr. 2021;40(5):2898-2913. https://doi.org/10.1016/j.clnu.2021.02.005.
15. Wischmeyer P., Carli F., Evans D., Guilbert S. et al. American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Nutrition Screening and Therapy Within a Surgical Enhanced Recovery Pathway. Anesthesia. Analgesia. 2018;126(6):1883-1895. https://doi.org/10.1213/ANE.0000000000002743.
16. Пасечник И.Н., Рыбинцев В.Ю., Маркелов К.М. Периоперационная нутритивная поддержка хирургических больных. Хирургия. Журнал им. Н.И. Пирогова. 2020;(10):95-103. https://doi.org/doi.org/10.17116/hirurgia202010195. Pasechnik IN, Rybintsev VYu, Markelov KM. Perioperative nutritional support for surgical patients. Pirogov Russian Journal of Surgery = Khirurgiya. Zurnal im. N.I. Pirogova. 2020;(10):95 103. (In Russ.).
17. Kondrup J., Rasmussen H. H., Hamberg O., et al. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. // Clin Nutr. - 2003. - Vol. 22. - 321-336. https://doi.org/10.1016/s0261-5614(02)00214-5.
18. Cederholm T., Jensen G.L., Correia M I T D et al. GLIM criteria for the diagnosis of malnutrition - A consensus report from the global clinical nutrition community. Clin Nutr. 2019;38(1):1-9. https://doi.org/10.1016/j.clnu.2018.08.002.
19. Symons TB, Sheffield-Moore M, Wolfe RR, Paddon-Jones D. A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc. 2009;109:1582-1586. https://doi.org/10.1016/j.jada.2009.06.369.
20. Paddon-Jones D, Campbell WW, Jacques PF, et al. Protein and healthy aging. Am J Clin Nutr. 2015;101:1339S-1345S. https://doi.org/10.3945/ajcn.114.084061.
21. Yao H., Bian X., Mao L. et al. Preoperative Enteral Nutritional Support in Patients Undergoing Hepatectomy for Hepatocellular Carcinoma: A Strengthening the Reporting of Observational Studies in Epidemiology Article. Medicine (Baltimore). 2015;94(46):e2006. https://doi.org/10.1097/MD.0000000000002006.
22. Brady M.C., Kinn S., Stuart P., Ness V. Preoperative fasting for adults to prevent perioperative complications (Review). Copyright © 2010 The Cochrane Collaboration. Published by JohnWiley & Sons, Ltd., 157 p.
23. Smith I, Kranke P, Murat I, Smith A, O’Sullivan G, Soreide E et al. Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology. Per- ioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol 2011, 28(8):556-569. https://doi.org/10.1097/EJA.0b013e3283495ba1.
24. Nygren J, Thorell A, Ljungqvist O: Preoperative oral carbohydrate therapy. Curr Opin Anaesthesiol 2015; 28:364-9. https://doi.org/10.1097/ACO.0000000000000192.
25. Смешной И.А., Пасечник И.Н., Тимашков Д.А., Онегин М.А., Чепарнов А.В. Влияние предоперационной пероральной углеводной нагрузки на периоперационный период (пилотное исследование). Consilium Medicum. 2019; 21 (8): 88-92. https://doi.org/10.26442/20751753.2019.8.190466. / Smeshnoi I.A., Pasechnik I.N., Timashkov D.A., Onegin M.A., Cheparnov A.V. Vliyaniye predoperatsionnoy peroralnoy uglevodnoy nagruzki na perioperatsionnyy period (pilotnoye issledovaniye). Consilium Medicum. 2019; 21 (8): 88-92. [in Russ].
26. Barlow R, Price P, Reid TD, Hunt S. et al. Prospective multicentre randomised controlled trial of early enteral nutrition for patients undergoing major upper gastrointestinal surgical resection. Clin Nutr. 2011;30(5):560-566. https://doi.org/10.1016/j.clnu.2011.02.006.
27. Lewis S.J., Andersen H.K., Thomas S. Early enteral nutrition within 24 h of intestinal surgery versus later commencement of feeding: a systematic review and meta-analysis. J Gastrointest Surg. 2009;13(3):569-75. https://doi.org/10.1007/s11605-008-0592-x.
28. Gianotti L., Besselink M.G., Sandini M. et al. Nutritional support and therapy in pancreatic surgery: A position paper of the International Study Group on Pancreatic Surgery (ISGPS). Surgery. 2018;164(5):1035-1048. https://doi.org/10.1016/j.surg.2018.05.040.
29. Bayramov N., Mammadova Sh. A review of the current ERAS guidelines for liver resection, liver transplantation and pancreatoduodenectomy. Ann Med Surg (Lond). 2022;82:104596. https://doi.org/10.1016/j.amsu.2022.104596.
30. Perinel J., Mariette C., Dousset B. et al. Early Enteral Versus Total Parenteral Nutrition in Patients Undergoing Pancreaticoduodenectomy: A Randomized Multicenter Controlled Trial (Nutri-DPC). Ann Surg. 2016;264(5):731-737. https://doi.org/10.1097/SLA.0000000000001896.
31. Lee S.H, Lee J.G. Early enteral nutrition still has advantages in patients undergoing pancreaticoduodenectomy. J Thorac Dis 2016;8(10):E1340-E1342. https://doi.org/10.21037/jtd.2016.10.65.
32. Godet T., Guerin R., Verlhac C. et al. Enteral Versus Total Parenteral Nutrition in Patients Undergoing Pancreaticoduodenectomy: A Randomized Multicenter Controlled Trial (Nutri-DPC): Let's Take a Closer Look at the Pancreas! Ann Surg. 2018;267(4):e70. https://doi.org/10.1097/SLA.0000000000002153.
33. Adiamah A., Ranat R., Gomez D. Enteral versus parenteral nutrition following pancreaticoduodenectomy: a systematic review and meta-analysis. HPB (Oxford). 2019;21(7):793-801. https://doi.org/10.1016/j.hpb.2019.01.005.
34. Takeda Y., Mise Y., Kishi Y. et al. Enteral versus parental nutrition after pancreaticoduodenectomy under enhanced recovery after surgery protocol: study protocol for a multicenter, open-label randomized controlled trial (ENE-PAN trial). Trials. 2022;23(1):917. https://doi.org/10.1186/s13063-022-06856-y.
According to the literature review, a nutritional support for patients after hepatopancreoduodenal surgery requires a differentiated approach. The paper presents data on the experience in providing nutritional support to this kind of patients. It is necessary to stress that nutritional risk screening should be performed prior to surgical intervention. The nutrition is recommended to be adjusted to protein and energy needs of the patient, taking into account concomitant diseases. Products for sip feeding are the method of choice. Enteral nutrition is preferable in the postoperative period. The nutritional support for patients undergoing pancreatoduodenal resection is increasingly recognized, and a randomized clinical trial is to be carried out to evaluate the effectiveness of enteral and parenteral nutrition. As a component of the enhanced recovery program, nutritional support can optimize outcomes in patients who have undergone hepatopancreatoduodenal resection. The nutritional status of a patient should be mandatorily assessed before surgery. Perioperative correction of nutritional status implies continuity and a multidisciplinary approach.
Keywords:
nutritional support, nutritional status, body mass index, hepatopancreatobiliary surgery, sip feeding, enteral nutrition