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Purpose. To compare the accuracy and complication rate of two different CTguided transthoracic needle biopsy techniques: fine needle aspiration and an automated core biopsy. Methods. Two consecutive series of respectively 42 fine needle aspiration and 50 core biopsies performed using 20 gauge fine needle aspiration and an automated 18 gauge biopsy device were compared in terms of their accuracy and complication rate. Results. Biopsy material was obtained in all 92 patients. For an adequacy of samples, a difference was found (90% vs 80.2%) between results obtained with the automated biopsy device and fine needle aspiration respectively. A statistically significant difference in obtaining specific histological diagnosis was found (p 0.006) between automated biopsy (78%) and FNAB (59.5%). There was also difference between two groups concerning rate of the pneumothorax, which reached 6% in core biopsy and 4.7% – in FNAB. Conclusion. Transthoracic CT-guided biopsy is a fast, safe and effective method for different localization of pulmonary lesions and provides useful diagnostic information in the majority of cases. Two methods give conclusive results, but more qualitative samples can be obtained in core biopsy, with no significant increase in complication rate.
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