Медицинская литература. Новинки

 

 

 

 

 

 

Возможности применения бесконтрастной МР-перфузии в дифференциальной диагностике опухоли мягких тканей

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Бесконтрастная МР-перфузия “меченых спинов артериальной крови” (“ASL-перфузия”) – это МР-технология качественной и количественной оценки перфузионных свойств тканей, основанная на маркировке спинов протонов артериальной крови радиочастотными импульсами и последующем их измерении при прохождении через зону интереса. Наибольший клинический опыт применения ASL-перфузии накоплен в диагностике заболеваний центральной нервной системы, однако в последние годы появились работы, показывающие эффективность использования данной методики в оценке перфузии скелетных мышц и диагностике опухолей мягких тканей.Представлены два клинических наблюдения (опухоль мягких тканей и посттравматические неопухолевые изменения), демонстрирующие возможности применения указанной методики для бесконтрастной оценки характера васкуляризации патологических изменений в мягких тканях бедра.

Ключевые слова:
опухоли мягких тканей, мультипараметрическая магнитно-резонансная томография, ASL-перфузия, soft tissue tumors, multiparametric magnetic resonance imaging, ASL-perfusion

Литература:
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15.Englund E.K., Rodgers Z.B., Langham M.C. et al. Measurement of Skeletal Muscle Perfusion Dynamics With Pseudo-Continuous Arterial Spin Labeling (pCASL): Assessment of Relative Labeling Efficiency at Rest and During Hyperemia, and Comparison to Pulsed Arterial Spin Labeling (PASL). Magn. Reson. Imaging. 2016; 44 (4): 929–939. https://doi.org/10.1002/jmri.25247
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18.Lin C.H., Hsieh, T.J., Chou Y.C., Chen C.K.H. Feasibility of Arterial Spin Labeling Magnetic Resonance Imaging for Musculoskeletal Tumors with Optimized Post-Labeling. Delay. Diagnostics. 2022; 12 (10): 2450. https://doi.org/10.3390/diagnostics12102450

Possibility of contrast-free MR-perfusion using in differential diagnosis of soft tissue tumor

Contrast-free MR-perfusion of ''labeled arterial blood spins'' (''ASL-perfusion'') is an MR-technology for qualitative and quantitative assessment of tissue perfusion properties based on of arterial blood proton spins labeling by radiofrequency pulses and their subsequent measurement when passing through the area of interest. The most of ASL-perfusion application clinical data referred to central nervous system diseases diagnostics, but some works showing the effectiveness of this technique in assessment of skeletal muscle perfusion and diagnostics of soft tissue tumors appeared recently.Two presented clinical cases (soft tissue tumor and post-traumatic benign changes) demonstrate the possibility of this technique usage to assess vascularization of pathological changes in hip soft tissues.

Keywords:
опухоли мягких тканей, мультипараметрическая магнитно-резонансная томография, ASL-перфузия, soft tissue tumors, multiparametric magnetic resonance imaging, ASL-perfusion